This Toneport thing is awesome,what makes it though is the Podfarm software that comes with it. I think the simulations are pretty close to the real amps and effects they've copied. Which are several old Fender and Marshall amps and some others... pedals like an old Ibanez Tube screamer and several others, echoplex type tape echos, or newer Boss type digital delays, 5-6 bass amps including an Ampeg SVT and cabinet and a Gallien Krueger that you hook into a Hartke 4x10 cab.
You probably need a modern computer and at least 4 GB of RAM, I've got 8 and run it and tons of other shit at the same time. And some good speakers, sounds great through the Klipsch Pro Media speakers I got awhile back, better than any guitar amp I've ever had.
The deal is you have to take the time and come up with your own presets, they have a few interesting ones but the stock tones are mostly pretty blah to me.
But it's like having a shitload of different amps and pedals I'd never be able to afford or have room for in a little thing that sits on top of your computer and you can find used ones for about $60...
I usually keep it pretty simple... here's the clean tele sound I mostly use....
Distorted but not super saturated... old Fender type amp,64 blackface? They can't use the exact names. With a tube screamer, reverb and an analog type echo box. To buy the old Tube Screamer it's modeled after is about $600 for an old beat up one.